PART1----試劑基礎(chǔ)信息：

LY2510924，LY2510924游離態(tài)，拮抗劑LY2510924，環(huán)肽，抑制劑
Product structure：

Product specifications：
1.CAS No：1088715-84-7
2.Molecular formula：C62H88N14O10
3.Molecular weight：1189.450
4.density：1.3±0.1 g/cm3
5.Packaging specification：1g、5g、10g, flexible packaging, including 100mg packaging and 500mg 1g and 5g large packaging
6.Dissolution conditions：Soluble in most organic solvents, such as DCM, DMF, DMSO, THF, etc., with good solubility in water

7.Stability：-1 year at 20 ° C, dry and dark.

8.Supplier：陜西新研博美生物科技有限公司?

PART2----試劑反應特點：

LY2510924是一種有效的、選擇性的CXCR4拮抗劑，特異性地阻止SDF-1與CXCR4的結(jié)合，IC50為0.079 nM；抑制SDF-1誘導的GTP結(jié)合，Kb值為0.38 nM。

LY2510924抑制SDF-1誘導的細胞遷移，IC50為0.26 nM；并抑制SDF-1/CXCR4介導的胞內(nèi)信號。LY2510924沒有明顯的激動活性。它對其他趨化因子受體如CCR1,CCR2,CXCR2和CXCRChemicalbook3在檢測濃度下沒有抑制活性，對5-羥色胺受體、多巴胺受體、opioidreceptors也沒有活性。

PART3----同類型試劑整理：

N-cyclopropene-L-Lysine
Octaphenylcyclotetrasiloxane
cyclo(L-Pro-L-Tyr)，Maculosin
1,7-Dioxa-4,10-diazacyclododecane
Cyclo(L-Phe-trans-4-hydroxy-L-Pro)
Cyclo(L-Leu-trans-4-hydroxy-L-Pro)
(3-Azidobutyl)cyclohexane
(Azidomethyl)-cyclohexane
N,N'-bis-(azide-PEG3)-chlorocyclohexenyl Cy7
N-(m-PEG4)-N'-(4-hydroxycyclohexyl-1-amido-PEG4)-Cy5
3-(trifluoromethyl)cyclohexan-1-ol
(Cyclo(Glu22-Lys26),Leu27)-pTH (1-31) amide (human)
1,1,3,3,5,5-Hexamethyl Cyclotrisilazane
1,1,3,3,5,5,7,7-Octamethyl Cyclotetrasilazane
Tris(Cyclohexylamino)Methylsilane

PART4----使用保存說明：

1.Matters?for use：

It is sensitive to light and temperature. In order to use the reagent effectively, the material should always be kept in a low temperature dry condition, away from light, and avoid frequent thawing and freezing.
2.storage conditions:
Store at - 20 ℃ as much as possible. If conditions permit, the material can be treated under inert gas to obtain better stability of the reagent.

以上陜西新研博美生物科技有限公司MISS.wu編輯的試劑信息僅用于科學研究或者工業(yè)應用等非醫(yī)療目的，非藥用，非食用。接受各種復雜定制服務，合成的Monodispersed PEGs除了有更多樣的基團還可以提供各種不同數(shù)量的PEG的產(chǎn)品。