1,2,3-三棕櫚酰甘油是在sn-1、sn-2、sn-3和sn-4處含有棕櫚酸的三?；视?，它抑制葡萄糖刺激的胰島素分泌，以濃度依賴的方式降低INS1細(xì)胞的活力。在鏈脲佐菌素誘導(dǎo)的糖尿病大鼠模型中，1,2,3-三棕櫚酰甘油的心肌水平升高了5倍以上含有依托泊苷的納米顆粒的基質(zhì)。含有1,2,3-三棕櫚酰甘油的配方已被用作化妝品的增稠劑和皮膚調(diào)理劑。

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艾美捷1,2,3-三棕櫚酰甘油基本參數(shù)：

正式名稱：1,1'，1''-（1,2,3-丙三醇）十六烷酸酯

CAS編號(hào)：555-44-2

同義詞：十六酸甘油酯、甘油三棕櫚酸酯、甘油三棕櫚酸酯、TG（16:0/16:0/16:0）、十六烷酰甘油

純度：≥85%

配方：結(jié)晶固體

溶解性：三氯甲烷：1 mg/ml

存儲(chǔ)：-20℃

穩(wěn)定性：≥4年

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艾美捷1,2,3-三棕櫚酰甘油相關(guān)文獻(xiàn)參考：

1. Lísa, M., and Hol?apek, M. Triacylglycerols profiling in plant oils important in food industry, dietetics and cosmetics using high-performance liquid chromatography-atmospheric pressure chemical ionization mass spectrometry. J. Chromatogr. A 1198-1199, 115-130 (2008).

2. Moffitt, J.H., Fielding, B.A., Evershed, R., et al. Adverse physicochemical properties of tripalmitin in beta cells lead to morphological changes and lipotoxicity in vitro. Diabetologia 48(9), 1819-1829 (2005).

3. Han, X., Abendschein, D.R., Kelley, J.G., et al. Diabetes-induced changes in specific lipid molecular species in rat myocardium. Biochem J. 352(Pt. 1), 79-89 (2000).

4. Reddy, L.H., Sharma, R.K., Chuttani, K., et al. Etoposide-incorporated tripalmitin nanoparticles with different surface charge: Formulation, characterization, radiolabeling, and biodistribution studies. AAPS J. 6(3), e23 (2004).

5. Johnson, W., Jr., and Panel, C.I.R.E. Final report on the safety assessment of trilaurin, triarachidin, tribehenin, tricaprin, tricaprylin, trierucin, triheptanoin, triheptylundecanoin, triisononanoin, triisopalmitin, triisostearin, trilinolein, trimyristin, trioctanoin, triolein, tripalmitin, tripalmitolein, triricinolein, tristearin, triundecanoin, glyceryl triacetyl hydroxystearate, glyceryl triacetyl ricinoleate, and glyceryl stearate diacetate. Int. J. Toxicol. 20(Suppl 4), 61-94 (2001).